During last AgileTour London 2020, I have personally facilitated an online session playing the game.
In the following screens you can have an idea on how you can arrange a session using Zoom (and breakout rooms) and Mural
The Virtual edition of the game is almost identical to the original, except the connectors that have been removed to make the solution easier. A specific set of cards have been developed and it is available in the original package in DriveThruCard.
Here is the link to the linkedIN posts where you can read some comments on the game from people participating as players.